Antibacterial effects of plants from lembang highland towards skin-infecting microorganisms

Authors

  • Anna Choirunnisa Universitas Jenderal Achmad Yani, Indonesia
  • Ita Nur Anisa Universitas Jenderal Achmad Yani, Indonesia
  • Dwi Yuliana Prasita Universitas Jenderal Achmad Yani, Indonesia
  • Suci Nar Vikasari Universitas Jenderal Achmad Yani, Indonesia

DOI:

https://doi.org/10.35335/midwifery.v11i1.1198

Keywords:

Antimicrobial, Moringa Leaf, Betel Leaf, Chinese pete Leaf, S. aureus, P. acnes

Abstract

Bacterial skin infection is a common infection in Indonesia. Staphylococcus aureus cause skin and soft tissue infections and Propionibacterium acnes causes acne (acnes vulgaris). Moringa oleifera, Piper betle, and Leucaena leucocephala leaves traditionally use as. This study aims is to evaluate antimicrobial activity of the ethanol extract of the leaves from Lembang highland against S. aureus and P. acnes. The extract of each leaves prepared using reflux in 50% ethanol and examination of antibacterial activity of the ethanol extract using the microdilution method in vitro. The results showed that the ethanol extracts of M.oleifera, P.betle, and L.leucocephala leaves had antibacterial activity against S. aureus and P. acnes with different minimum inhibitory concentrations. The greatest antibacterial activity against S.aureus was shown by the ethanol extract of moringa leaves (MIC = 1024 µg/ml), where the greatest antibacterial activity against P. acnes was possessed by the ethanol extract of betel leaves (MIC = 512 µg/ml).

Downloads

Download data is not yet available.

References

Abadallah, M. S., & Ali, M. (2019). Antibacterial activity of Moringa oleifera leaf extracts against bacteria isolated from patients attending general Sani Abacha specialist hospital damaturu. J. Allied Pharm. Sci, 1(March), 61–66.

Angestia, W., Ningrum, V., Lee, T. L., Lee, S.-C., & Bakar, A. (2020). Antibacterial activities of moringa olifiera freeze dried extract on staphylococcus aureus. Journal of Dentomaxillofacial Science, 5(3), 154. https://doi.org/10.15562/jdmfs.v5i2.1043

Chassagne, F., Samarakoon, T., Porras, G., Lyles, J. T., Dettweiler, M., Marquez, L., Salam, A. M., Shabih, S., Farrokhi, D. R., & Quave, C. L. (2021). A Systematic Review of Plants With Antibacterial Activities: A Taxonomic and Phylogenetic Perspective. Frontiers in Pharmacology, 11(January). https://doi.org/10.3389/fphar.2020.586548

Choirunnisa, A., & Sutjiatmo, A. B. (2017). Pengaruh kombinasi ekstrak etanol herba cecendet (Physalis angulata l.) dengan beberapa antibiotik terhadap bakteri Staphylococcus aureus dan Klebsiella pneumonie. Kartika : Jurnal Ilmiah Farmasi, 5(2), 50. https://doi.org/10.26874/kjif.v5i2.114

Ermawati, F. U., Sari, R., Putri, N. P., Rohmawati, L., Kusumawati, D. H., Munasir, & Supardi, Z. A. I. (2021). Antimicrobial activity analysis of Piper betle Linn leaves extract from Nganjuk, Sidoarjo and Batu against Escherichia coli, Salmonella sp., Staphylococcus aureus and Pseudomonas aeruginosa. Journal of Physics: Conference Series, 1951(1). https://doi.org/10.1088/1742-6596/1951/1/012004

Guimarães, A. C., Meireles, L. M., Lemos, M. F., Guimarães, M. C. C., Endringer, D. C., Fronza, M., & Scherer, R. (2019). Antibacterial Activity of Terpenes and Terpenoids Present in Essential Oils. Molecules, 24(13), 2471. https://doi.org/10.3390/molecules24132471

Hidayah, N., Fitriansyah, S. N., Aulifa, D. L., Dewi, S., & Barkah, W. (2020). Determination of Total Phenolic, Flavonoid Content and Antioxidant Activity of Campolay (Pouteria campechiana (Kunth) Baehni) Extract. 9(13), 876–886. https://doi.org/10.2991/ahsr.k.200523.026

Hidayat, R. (2018). HUBUNGAN KEBERSIHAN DIRI (PERSONAL HYGIENE) DENGAN KEJADIAN PENYAKIT DERMATOFITOSIS DI DESA LERENG WILAYAH KERJA PUSKESMAS KUOK. Ners, 2(1), 86–94.

Hidayat, T., Hamzah, B., & Jura, M. R. (2020). Determination of Total Flavonoid Contents and Antioxidant Activity of Leucaena Leucocephala Leaves’s Extract. Jurnal Akademika Kimia, 9(2), 70–77. https://doi.org/10.22487/j24775185.2020.v9.i2.pp70-77

Ibrahim, A., & Kuncoro, H. (2012). IDENTIFIKASI METABOLIT SEKUNDER DAN AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SUNGKAI (Peronema canescens JACK.) TERHADAP BEBERAPA BAKTERI PATOGEN. Journal Of Tropical Pharmacy And Chemistry, 2(1), 8–18. https://doi.org/10.25026/jtpc.v2i1.43

Indonesia, K. K. R. (2017). Farmakope Herbal Indonesia. In Kementrian Kesehatan RI. https://doi.org/10.1201/b12934-13

Jiménez, M. B., Peraza, J. A. L., López, J. L., Rivero, D. O., & Ucán-Rodríguez, F. (2022). ANTIMICROBIAL ACTIVITY OF MORINGA OLEIFERA LEAVES. Novel Techniques in Nutrition and Food Science, 6(3), NTNF. 000635. https://doi.org/10.31031/NTNF.2022.06.000635

Katuuk, R. H. H., Wanget, S. A., & Tumewu, P. (2019). PENGARUH PERBEDAAN KETINGGIAN TEMPAT TERHADAP KANDUNGAN METABOLIT SEKUNDER PADA GULMA BABADOTAN (Ageratum conyzoides L.). Cocos, 1(4), 1–6.

Kurniawan, K., Pertiwi, A. T., & Lestari, I. T. (2021). Analisa Absorbansi Kadar Flavonoid Total Ekstrak Maserasi Daun Sirih Hijau (Piper betle L.). Pharmaceutical Journal of Islamic Pharmacy, 5(1), 80. https://doi.org/10.21111/pharmasipha.v5i1.5707

Lorian, V. (2005). Antibiotics in Laboratory Medicine (V. Lorian (ed.); 5th ed.). Lippincott Williams & Wilkins.

Phensri, P., Thummasema, K., Sukatta, U., Morand, S., & Pruksakorn, C. (2022). In Vitro Antimicrobial Activity of Piper betle Leaf Extract and Some Topical Agents against Methicillin-Resistant and Methicillin-Susceptible Staphylococcus Strains from Canine Pyoderma. Animals, 12(22). https://doi.org/10.3390/ani12223203

Rosida, D. F., Djajati, S., Nilamayu, Z. A., & Rosida. (2018). Antibacterial Activity of Leucaena leucocephala Extracts on Growth of Escherichia coli . Advanced Science Letters, 23(12), 12268–12271. https://doi.org/10.1166/asl.2017.10618

Sadiah, H. H., Cahyadi, A. I., & Windria, S. (2022). Kajian Daun Sirih Hijau (Piper betle L) Sebagai Antibakteri. Jurnal Sain Veteriner, 40(2), 128. https://doi.org/10.22146/jsv.58745

Scalbert, A. (1991). Antimicrobial properties of tannins. Phytochemistry, 30(12), 3875–3883. https://doi.org/10.1016/0031-9422(91)83426-L

Sibero, H. T., Sirajudin, A., & Anggraini, D. (2019). Prevalensi dan Gambaran Epidemiologi Akne Vulgaris di Provinsi Lampung The Prevalence and Epidemiology of Acne Vulgaris in Lampung. Jurnal Farmasi Komunitas, 3(2), 62–68

Downloads

Published

2023-04-18

How to Cite

Choirunnisa, A. (2023) “Antibacterial effects of plants from lembang highland towards skin-infecting microorganisms”, Science Midwifery, 11(1), pp. 129–134. doi: 10.35335/midwifery.v11i1.1198.

Most read articles by the same author(s)