Antioxidant activity of brown algae extract (Sargassum sp): A review

Authors

  • Pramudita Riwanti Universitas Hang Tuah, Indonesia
  • Mahmiah Mahmiah Universitas Hang Tuah, Indonesia
  • Kiki Juniar Universitas Hang Tuah, Indonesia

DOI:

https://doi.org/10.35335/midwifery.v11i6.1420

Keywords:

Antioxidant, DPPH, IC50, Sargassum SP, Spectrofotometer UV-VIS

Abstract

Free radicals are compounds that trigger oxidative stress and harm human health. Uncontrolled oxidative stress causes several degenerative diseases. Antioxidants are needed to prevent or reduce oxidative stress. One of the plants with a high content of antioxidant compounds is brown algae (Sargassum sp). The study aimed to examine Sargassum sp.'s antioxidant activity, which is expressed in the IC50 value using the DPPH method as measured by a UV-Vis spectrophotometer. It is a narrative review, with literature searches from the Science Direct, Pubmed, and Google Scholar databases. The results showed that the methanol extract of Sargassum sp. has strong antioxidant activity consisting of phenolic compounds, flavonoids, and carotenoids. This review concludes that Sargassum sp extract has antioxidant activity.

Downloads

Download data is not yet available.

References

Arsianti, A., Bahtiar, A., Wangsaputra, V. K., Azizah, N. N., Fachri, W., Nadapdap, L. D., Fajrin, A. M., Tanimoto, H., & Kakiuchi, K. (2020). Phytochemical composition and evaluation of marine algal Sargassum polycystum for antioxidant activity and in vitro cytotoxicity on hela cells. Pharmacognosy Journal, 12(1), 88–94. https://doi.org/10.5530/pj.2020.12.14

Baek, S. H., Cao, L., Jeong, S. J., Kim, H. R., Nam, T. J., & Lee, S. G. (2021). The Comparison of Total Phenolics, Total Antioxidant, and Anti-Tyrosinase Activities of Korean Sargassum Species. Journal of Food Quality, 2021. https://doi.org/10.1155/2021/6640789

Balasubramaniam, V., June Chelyn, L., Vimala, S., Mohd Fairulnizal, M. N., Brownlee, I. A., & Amin, I. (2020). Carotenoid composition and antioxidant potential of Eucheuma denticulatum, Sargassum polycystum and Caulerpa lentillifera. Heliyon, 6(8). https://doi.org/10.1016/j.heliyon.2020.e04654

Catarino, M. D., Silva-Reis, R., Chouh, A., Silva, S., Braga, S. S., Silva, A. M. S., & Cardoso, S. M. (2023). Applications of Antioxidant Secondary Metabolites of Sargassum spp. Marine Drugs, 21(3), 172.

de Menezes, B. B., Frescura, L. M., Duarte, R., Villetti, M. A., & da Rosa, M. B. (2021). A critical examination of the DPPH method: Mistakes and inconsistencies in stoichiometry and IC50 determination by UV–Vis spectroscopy. Analytica Chimica Acta, 1157. https://doi.org/10.1016/j.aca.2021.338398

Edison, E., Diharmi, A., Ariani, N. M., & Ilza, M. (2020). Komponen bioaktif dan aktivitas antioksidan ekstrak kasar Sargassum plagyophyllum. Jurnal Pengolahan Hasil Perikanan Indonesia, 23(1), 58–66.

Firdaus, M. (2013). Antioxidant Activity Index of Brown Seaweed (Sargassum aquifolium) Extract. Indonesian Journal of Fishery Product Processing, 16(1), 42–47.

Gazali, M., Zamani, N., Nurjanah, N., Zulfadhli, Z., & Safutra, E. (2018). Eksplorasi potensi senyawa bioaktif makroalga laut Sargassum sp asal Pesisir Aceh Barat sebagai agen antioksidan. Journal of Aceh Aquatic Sciences, 1(1).

Jimenez-Lopez, C., Pereira, A. G., Lourenço-Lopes, C., Garcia-Oliveira, P., Cassani, L., Fraga-Corral, M., Prieto, M. A., & Simal-Gandara, J. (2021). Main bioactive phenolic compounds in marine algae and their mechanisms of action supporting potential health benefits. Food Chemistry, 341. https://doi.org/10.1016/j.foodchem.2020.128262

Kaczorová, D., Karalija, E., Dahija, S., Bešta-Gajević, R., Parić, A., & Ćavar Zeljković, S. (2021). Influence of extraction solvent on the phenolic profile and bioactivity of two achillea species. Molecules, 26(6). https://doi.org/10.3390/molecules26061601

Leyane, T. S., Jere, S. W., & Houreld, N. N. (2022). Oxidative Stress in Ageing and Chronic Degenerative Pathologies: Molecular Mechanisms Involved in Counteracting Oxidative Stress and Chronic Inflammation. In International Journal of Molecular Sciences (Vol. 23, Issue 13). MDPI. https://doi.org/10.3390/ijms23137273

Manteu, S. H., & Nurjanah, N. T. (2018). Karakteristik rumput laut cokelat (Sargassum policystum dan Padina minor) dari perairan Pohuwato Provinsi Gorontalo. Jurnal Pengolahan Hasil Perikanan Indonesia, 21(3), 396–405.

Nawaz, H., Shad, M. A., Rehman, N., Andaleeb, H., & Ullah, N. (2020). Effect of solvent polarity on extraction yield and antioxidant properties of phytochemicals from bean (Phaseolus vulgaris) seeds. Brazilian Journal of Pharmaceutical Sciences, 56. https://doi.org/10.1590/s2175-97902019000417129

Noorjahan, A., Aiyamperumal, B., & Anantharaman, P. (2019). Characterization and Biochemical Properties of Brown Seaweed Sargassum Tenerrimum (J. agardh). International Journal of Pharmacy and Biological Sciences-IJPBS TM, 2, 9. https://doi.org/10.21276/ijpbs.2019.9.2.34

Olugbami, J. O., Gbadegesin, M. A., & Odunola, O. A. (2014). In vitro evaluation of the antioxidant potential, phenolic and flavonoid contents of the stem bark ethanol extract of Anogeissus leiocarpus HHS Public Access. In Afr J Med Med Sci (Vol. 43, Issue 1).

Palanisamy, S., Vinosha, M., Marudhupandi, T., Rajasekar, P., & Prabhu, N. M. (2017). Isolation of fucoidan from Sargassum polycystum brown algae: Structural characterization, in vitro antioxidant and anticancer activity. International Journal of Biological Macromolecules, 102, 405–412. https://doi.org/10.1016/j.ijbiomac.2017.03.182

Panche, A. N., Diwan, A. D., & Chandra, S. R. (2016). Flavonoids: An overview. In Journal of Nutritional Science (Vol. 5). Cambridge University Press. https://doi.org/10.1017/jns.2016.41

Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., Arcoraci, V., Squadrito, F., Altavilla, D., & Bitto, A. (2017). Oxidative Stress: Harms and Benefits for Human Health. In Oxidative Medicine and Cellular Longevity (Vol. 2017). Hindawi Limited. https://doi.org/10.1155/2017/8416763

Platzer, M., Kiese, S., Tybussek, T., Herfellner, T., Schneider, F., Schweiggert-Weisz, U., & Eisner, P. (2022). Radical Scavenging Mechanisms of Phenolic Compounds: A Quantitative Structure-Property Relationship (QSPR) Study. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.882458

Polo, L. K., & Chow, F. (2022). Variation of antioxidant capacity and antiviral activity of the brown seaweed Sargassum filipendula (Fucales, Ochrophyta) under UV radiation treatments. Applied Phycology, 3(1), 260–273.

Rohimat, R., Widowati, I., & Trianto, A. (2014). Aktivitas antioksidan ekstrak metanol rumput laut coklat (Turbinaria conoides dan sargassum cristaefolium) yang dikoleksi dari pantai rancabuaya garut jawa barat. Journal of Marine Research, 3(3), 304–313.

Salehi, B., Martorell, M., Arbiser, J. L., Sureda, A., Martins, N., Maurya, P. K., Sharifi-Rad, M., Kumar, P., & Sharifi-Rad, J. (2018). Antioxidants: Positive or negative actors? In Biomolecules (Vol. 8, Issue 4). MDPI AG. https://doi.org/10.3390/biom8040124

Sami, F. J., Soekamto, N. H., Firdaus, F., & Latip, J. (2019). Uji Aktivitas Antioksidan Ekstrak Alga Coklat Sargassum polycystum Dan Turbinaria deccurens Asal Pulau Dutungan Sulawesi Selatan Terhadap Radikal DPPH. Jurnal Kimia Riset, 4(1), 1–6.

Sanger, G., Wonggo, D., Montolalu, L., & Dotulong, V. (2022). Pigments constituents, phenolic content and antioxidant activity of brown seaweed Sargassum sp. IOP Conference Series: Earth and Environmental Science, 1033(1), 12057.

Sedjati, S., Supriyantini, E., Ridlo, A., Soenardjo, N., & Santi, V. Y. (2018). Kandungan Pigmen, Total Fenolik Dan Aktivitas Antioksidan Sargassum sp. Jurnal Kelautan Tropis, 21(2), 137. https://doi.org/10.14710/jkt.v21i2.3329

Sharifi-Rad, M., Anil Kumar, N. V., Zucca, P., Varoni, E. M., Dini, L., Panzarini, E., Rajkovic, J., Tsouh Fokou, P. V., Azzini, E., Peluso, I., Prakash Mishra, A., Nigam, M., El Rayess, Y., Beyrouthy, M. El, Polito, L., Iriti, M., Martins, N., Martorell, M., Docea, A. O., … Sharifi-Rad, J. (2020). Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases. In Frontiers in Physiology (Vol. 11). Frontiers Media S.A. https://doi.org/10.3389/fphys.2020.00694

Sivasankara Narayani, S., Saravanan, S., Bharathiaraja, S., & Mahendran, S. (2016). Extraction, partially purification and study on antioxidant property of fucoxanthin from Sargassum cinereum J. Agardh. Available Online Www.Jocpr.Com Journal of Chemical and Pharmaceutical Research, 8(3), 610–616. www.jocpr.com

Sobuj, M. K. A., Islam, M. A., Islam, M. S., Islam, M. M., Mahmud, Y., & Rafiquzzaman, S. M. (2021). Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-98461-3

Veerichetty, V., & Rafi, A. S. M. (2022). Comparative antioxidant capacity of fucoidan batches extracted from Sargassum species. AIP Conference Proceedings, 2446(1).

Yegdaneh, A., Mehdinezhad, N., Ghannadi, A., & Yegdaneh, A. (2016). Phytochemical and biological evaluation of some Sargassum species from Persian Gulf. In Research in Pharmaceutical Sciences (Vol. 11, Issue 3).

Yousefi, N., & Abbasi, S. (2022). Food proteins: Solubility & thermal stability improvement techniques. In Food Chemistry Advances (Vol. 1). Elsevier Ltd. https://doi.org/10.1016/j.focha.2022.100090

Zaidan, S., Abdillah, S., Pratami, D. K., & Utami, S. A. (2022). Nanoparticles of brown seaweed (sargassum polycystum) extract and its antioxidant activity in rats fed high-fat diet. Int J App Pharm, 14(4), 186–191.

Downloads

Published

2024-02-28

How to Cite

Riwanti, P., Mahmiah, M. and Juniar, K. . (2024) “Antioxidant activity of brown algae extract (Sargassum sp): A review”, Science Midwifery, 11(6), pp. 962–970. doi: 10.35335/midwifery.v11i6.1420.